Bioactivity:

Imatinib mesylate is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 _M, 0.1 _M and 0.1 _M for v-Abl, c-Kit and PDGFR, respectively).

CAS nr:

220127-57-1

Purity:

98%

Molecular Weight:

589,71

SMILES:

CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1

Formula:

C29H31N7O�CH4SO3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Autophagy,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling

Target:

PDGFR,PDGFR,Autophagy,c-Kit,Bcr-Abl,Bcr-Abl,Bcr-Abl