Bioactivity:

NSC 663284 is a cell-permeable and irreversible Cdc25 dual specificity phosphatase inhibitor (IC50 for Cdc25B2: 0.21 _M). NSC 663284 inhibits NSD2 (IC50 of 170 nM) through direct interaction with the catalytic SET domain (Kd of 370 nM). NSC 663284 display

CAS nr:

383907-43-5

Purity:

98%

Molecular Weight:

321,76

SMILES:

O=C(C(Cl)=C1NCCN2CCOCC2)C3=C(N=CC=C3)C1=O

Formula:

C15H16ClN3O3

Pathway:

Metabolism,Membrane transporter/Ion channel

Target:

Calcium Channel,Calcium Channel