Bioactivity:

1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 _M, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 _M). 1-Naphthohydroxamic acid does not increase global histone H4

CAS nr:

6953-61-3

Purity:

98%

Molecular Weight:

187,19

SMILES:

ONC(=O)C1=CC=CC2=CC=CC=C12

Formula:

C11H9NO2

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

HDAC,HDAC