Bioactivity:

(Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).

CAS nr:

1641574-26-6

Purity:

98%

Molecular Weight:

543,93

SMILES:

O=S(NC1=NOC=C1)(C2=CC(C=CC(N3C4=CC(F)=C(C=C4OC)C5=CC(Cl)=CC(F)=C5)=O)=C3C=C2)=O.[Racemate]

Formula:

C25H16ClF2N3O5S

Pathway:

Others

Target:

Others