Bioactivity:

Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin h

CAS nr:

1281870-42-5

Purity:

98%

Molecular Weight:

394,86

SMILES:

O=C(N/N=C/C1=CC=C2N=CC=NC2=C1)[C@H](N)CC3=CNC4=C3C=CC=C4.Cl

Formula:

C20H19ClN6O

Pathway:

MAPK,GPCR/G Protein,Cell Cycle/Checkpoint,Apoptosis

Target:

Ras,Ras,Rho,Apoptosis