Bioactivity:

ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM).

CAS nr:

852808-04-9

Purity:

98%

Molecular Weight:

813,43

SMILES:

CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1

Formula:

C42H45ClN6O5S2

Pathway:

Apoptosis,Autophagy,Autophagy

Target:

BCL,Autophagy,Mitophagy