Bioactivity:

INDY is a ATP-competitive inhibitor of Dyrk1A and Dyrk1B (IC50s: 0.24 _M and 0.23 _M). INDY sharply causes the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma cell lines and neural progenitor cells. INDY binds in the ATP poc

CAS nr:

1169755-45-6

Purity:

98%

Molecular Weight:

235,3

SMILES:

CC(/C=C1SC2=CC=C(O)C=C2N\1CC)=O

Formula:

C12H13NO2S

Pathway:

Tyrosine Kinase/Adaptors,Cell Cycle/Checkpoint

Target:

DYRK,DYRK