Bioactivity:

SKI2852 is a highly Potent, selective, and orally bioavailable inhibitor of 11_-Hydroxysteroid Dehydrogenase Type 1 (11_-HSD1). hHSD1 IC50 = 2.9nM; mHSD1 IC50 = 1.6nM.

CAS nr:

1346554-47-9

Purity:

98%

Molecular Weight:

543,66

SMILES:

O=C(C1=NC(N2CCN(C[C@H]2C)C3=CC=C(C=C3F)S(C)(=O)=O)=NC=C1)N[C@@H]4[C@@H]5C[C@H]6C[C@](C5)(O)C[C@@H]4C6

Formula:

C27H34FN5O4S

Pathway:

Target: