Bioactivity:

Marizomib suppresses the CT-L (_5), CT-T-laspase-like (C-L, _1), and trypsin-like (T-L, _2) activities of the 20S proteasome (IC50=3.5, 28, and 430 nM, respectively). Marizomib is a second-generation, irreversible, brain-penetrant inhibitor of pan-proteas

CAS nr:

437742-34-2

Purity:

98%

Molecular Weight:

313,78

SMILES:

O=C([C@H](CCCl)[C@]1(C)O2)N[C@@]1([C@H]([C@@H]3C=CCCC3)O)C2=O

Formula:

C15H20ClNO4

Pathway:

Others

Target:

Others