Bioactivity:

CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.

CAS nr:

2095616-82-1

Purity:

98%

Molecular Weight:

569,67

SMILES:

Cc1cc(cc(n1)C#Cc1ccc2c3c(oc2c1)C(C)(C)c1cc(NS(C)(=O)=O)ccc1C3=O)C(=O)NC(C)(C)C

Formula:

C32H31N3O5S

Pathway:

Tyrosine Kinase/Adaptors

Target:

Trk receptor