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Bioactivity:
NSC 207895 suppresses MDMX with IC50 of 2.5 _M, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
CAS nr:
58131-57-0
Purity:
98%
Molecular Weight:
279,25
SMILES:
CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]
Formula:
C11H13N5O4
Pathway:
Apoptosis,Apoptosis
Target:
Mdm2,p53