Pralatrexate T6120
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
CAS nr:
146464-95-1
Purity:
98%
Molecular Weight:
477,47
SMILES:
C#CCC(Cc1cnc2c(n1)c(nc(n2)N)N)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Formula:
C23H23N7O5
Pathway:
Cell Cycle/Checkpoint,DNA Damage/DNA Repair,Tyrosine Kinase/Adaptors,Metabolism,Cell Cycle/Checkpoint,Apoptosis
Target:
DHFR,DHFR,TAM Receptor,DHFR,Antifolate,Apoptosis
