Bioactivity:

Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).

CAS nr:

2070014-82-1

Purity:

98%

Molecular Weight:

691,82

SMILES:

CS(=O)(O)=O.C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O.CS(=O)(O)=O

Formula:

C30H41N7O8S2

Pathway:

JAK/STAT signaling,Tyrosine Kinase/Adaptors,Angiogenesis

Target:

EGFR,EGFR,EGFR