Bioactivity:

XL888 is an ATP-competitive inhibitor of Hsp90 ( IC50: 24 nM). Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis. Through this action, specific clie

CAS nr:

1149705-71-4

Purity:

98%

Molecular Weight:

503,6

SMILES:

CC[C@@H](C)Nc1cc(C(=O)N[C@@H]2C[C@@H]3CC[C@H](C2)N3c2ccc(cn2)C(=O)C2CC2)c(C)cc1C(N)=O

Formula:

C29H37N5O3

Pathway:

Metabolism,Cytoskeletal Signaling

Target:

HSP,HSP