Bioactivity:

SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).

CAS nr:

891494-64-7

Purity:

98%

Molecular Weight:

376,25

SMILES:

Cn1cc(cn1)c1c2nc(c(c(n2nc1)N)Br)[C@H]1CCCNC1

Formula:

C15H18BrN7

Pathway:

Cell Cycle/Checkpoint,Cell Cycle/Checkpoint

Target:

Chk,CDK