Bioactivity:

Gemcitabine is a DNA synthesis inhibitor that can inhibit the growth of MIAPaCa2, BxPC3 and Capan2 cells (IC50s: 40/18/12 nM). It can also induce autophagy.

CAS nr:

95058-81-4

Purity:

98%

Molecular Weight:

263,2

SMILES:

Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1

Formula:

C9H11F2N3O4

Pathway:

Cell Cycle/Checkpoint,DNA Damage/DNA Repair,DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Apoptosis,Autophagy

Target:

Nucleoside Antimetabolite/Analog,Nucleoside Antimetabolite/Analog,DNA/RNA Synthesis,DNA/RNA Synthesis,Apoptosis,Autophagy