Bioactivity:

DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit NF-_B activity.

CAS nr:

2242470-43-3

Purity:

98%

Molecular Weight:

356,42

SMILES:

O=C1N(C2=CC=C(CC3=CC=NC=C3)C=C2)C(C4C5C(C6)C6C(C=C5)C14)=O

Formula:

C23H20N2O2

Pathway:

Others,NF-_b,Apoptosis

Target:

Others,NF-_B,Apoptosis