Bioactivity:

SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.

CAS nr:

1561178-17-3

Purity:

98%

Molecular Weight:

618,57

SMILES:

CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12

Formula:

C28H40BrN7O4

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase