Bioactivity:

Capmatinib xHCl is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor,�potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 n

CAS nr:

1029714-89-3

Purity:

98%

Molecular Weight:

448,9

SMILES:

Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1

Formula:

C23H18ClFN6O

Pathway:

Tyrosine Kinase/Adaptors

Target:

c-Met/HGFR