Bioactivity:

PROTAC-12 is a SirReal-based PROTAC which induces isotype-selective Sirt2 degradation, resulting in the hyperacetylation of the microtubule network coupled with enhanced process elongation.

CAS nr:

T34167

Purity:

98%

Molecular Weight:

852,94

SMILES:

O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CCCCNC(COC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)N=N3)=C2)S1)CSC7=NC(C)=CC(C)=N7

Formula:

C40H40N10O8S2

Pathway:

Target: