Bioactivity:

PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110_(IC50=5.8 nM) and p110_(IC50=76 nM).

CAS nr:

372196-67-3

Purity:

98%

Molecular Weight:

452,28

SMILES:

CN(\N=C\c1cnc2ccc(Br)cn12)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O

Formula:

C16H14BrN5O4S

Pathway:

PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair,Apoptosis

Target:

PI3K,DNA-PK,DNA-PK,Apoptosis