Bioactivity:

Tacrolimus can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase.

CAS nr:

104987-11-3

Purity:

98%

Molecular Weight:

804,02

SMILES:

CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC

Formula:

C44H69NO12

Pathway:

PI3K/Akt/mTOR signaling,Microbiology/Virology,Microbiology/Virology,Metabolism,Others,Autophagy

Target:

mTOR,Antibacterial,Antibiotic,Phosphatase,Others,Autophagy