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Bioactivity:
Compound 23 selectively induces degradation of BRAF-V600E but not wildtype BRAF.
CAS nr:
2417296-84-3
Purity:
98%
Molecular Weight:
1001,07
SMILES:
CCCS(=O)(NC1=CC=C(F)C(N2C=C(C3=CN=CN=C3)C4=NC(N(C5CCN(C(CCOCCOCCOCCNC6=CC=CC(C(N7C(CC8)C(NC8=O)=O)=O)=C6C7=O)=O)CC5)C)=CC=C42)=C1F)=O
Formula:
C48H54F2N10O10S
Pathway:
MAPK
Target:
Raf