Bioactivity:

IT-901 is an orally active and effective inhibitor of NF-_B subunit c-Rel (IC50s: 0.1 ﾵM, 3 _M for NF-_B DNA binding and c-Rel DNA binding, respectively). IT-901 has the potential for human lymphoid tumors, and ameliorate graft-versus-host disease.

CAS nr:

1584121-99-2

Purity:

98%

Molecular Weight:

342,37

SMILES:

O=C(/C(C(N1)=O)=C\C2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S

Formula:

C17H14N2O4S

Pathway:

NF-_b

Target:

NF-_B