Bioactivity:

Dasatinib is a potent inhibitor of the Bcr-Abl and Src family (IC50s: 0.6, 0.8, 79 and 37 nM for Abl, Src, c-Kit, and c-KitD816V, respectively).

CAS nr:

302962-49-8

Purity:

98%

Molecular Weight:

488,01

SMILES:

Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1

Formula:

C22H26ClN7O2S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Autophagy,Apoptosis,Cytoskeletal Signaling,Tyrosine Kinase/Adaptors

Target:

Bcr-Abl,Bcr-Abl,Src,Src,Autophagy,Apoptosis,Bcr-Abl,c-Kit