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Bioactivity:
AVN-944(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
CAS nr:
297730-17-7
Purity:
98%
Molecular Weight:
477,51
SMILES:
c1(ocnc1)c1c(cc(cc1)NC(=O)Nc1cc(ccc1)[C@@H](NC(=O)O[C@@H](CC#N)CC)C)OC
Formula:
C25H27N5O5
Pathway:
Metabolism
Target:
Dehydrogenase