Bioactivity:

AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in prometaphase, followed by a surge in apoptosis. AAPK-25 targets Aurora-A/-B/-C with Kd values ranging from 23-289 nM, a

CAS nr:

2247919-28-2

Purity:

98%

Molecular Weight:

442,32

SMILES:

ClC1=CC(C(NC2=CC=C(C=C(C(NC3=NC=CS3)=O)C=C4)C4=C2)=O)=CC=C1Cl

Formula:

C21H13Cl2N3O2S

Pathway:

Others

Target:

Others