Bioactivity:

Pemetrexed, a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).

CAS nr:

137281-23-3

Purity:

98%

Molecular Weight:

427,41

SMILES:

Nc1nc(=O)c2c([nH]cc2CCc2ccc(cc2)C(=O)N[C@@H](CCC(=O)O)C(=O)O)[nH]1

Formula:

C20H21N5O6

Pathway:

DNA Damage/DNA Repair,Metabolism,Cell Cycle/Checkpoint,Autophagy,Cell Cycle/Checkpoint,DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

DHFR,DHFR,DHFR,Autophagy,Antifolate,DNA/RNA Synthesis,DNA/RNA Synthesis