Bioactivity:

L002 binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain, blocks histone acetylation and p53 acetylation, and inhibits STAT3 activation. L002 has the potential for hypertension_induced cardiac hypertrophy and fibrogenesis t

CAS nr:

321695-57-2

Purity:

98%

Molecular Weight:

321,35

SMILES:

O=C1C(C)=C/C(C=C1C)=N\OS(=O)(C2=CC=C(OC)C=C2)=O

Formula:

C15H15NO5S

Pathway:

Stem Cells,JAK/STAT signaling,Others,Chromatin/Epigenetic

Target:

STAT,STAT,Others,Histone Acetyltransferase