Bioactivity:

The biological activity of Jervine is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the

CAS nr:

469-59-0

Purity:

98%

Molecular Weight:

425,61

SMILES:

O=C1C2=C(C)[C@]3(CC[C@H]2[C@@H]2CC=C4C[C@H](CC[C@]4(C)[C@@H]12)O)O[C@@H]1C[C@@H](CN[C@H]1[C@H]3C)C

Formula:

C27H39NO3

Pathway:

Stem Cells,GPCR/G Protein,Stem Cells

Target:

Smo,Hedgehog/Smoothened,Hedgehog/Smoothened