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Bioactivity:
APY29 is an allosteric modulator of IRE1_; inhibits IRE1_ autophosphorylation (IC50 = 280 nM) and activates IRE1_ RNase activity.
CAS nr:
1216665-49-4
Purity:
98%
Molecular Weight:
332,36
SMILES:
C1CC1c1cc(n[nH]1)Nc1nc(ncc1)Nc1cc2c(cc1)nc[nH]2
Formula:
C17H16N8
Pathway:
Cell Cycle/Checkpoint
Target:
IRE1