Bioactivity:

LMT-28 is an orally active and the first synthetic IL-6 inhibitor. That functions through direct binding to gp130. LMT-28 displays low toxicity and selectively inhibits IL-6�induced phosphorylation of STAT3, JAK2, and gp130.

CAS nr:

1239600-18-0

Purity:

98%

Molecular Weight:

311,42

SMILES:

O=C1OC[C@H](C(C)C)N1C([C@@H](C)[C@H](O)C(CCCCC)=C)=O

Formula:

C17H29NO4

Pathway:

Others

Target:

Others