(S)-crizotinib T6357
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
(S)-crizotinib_IC50 of 72 nM_, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.
CAS nr:
1374356-45-2
Purity:
98%
Molecular Weight:
450,34
SMILES:
C[C@@H](c1c(ccc(c1Cl)F)Cl)Oc1c(ncc(c1)c1cn(nc1)C1CCNCC1)N
Formula:
C21H22Cl2FN5O
Pathway:
DNA Damage/DNA Repair,DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Apoptosis
Target:
MTH1,DNA/RNA Synthesis,DNA/RNA Synthesis,Apoptosis
