Bioactivity:

Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting in the down-regulation of expression of Cdk4.

CAS nr:

98665-19-1

Purity:

98%

Molecular Weight:

572,7

SMILES:

[H][C@@]12CC(=O)C3=C(C(=O)[C@@H](OC(C)=O)[C@]4(C)[C@H](CC(=O)[C@@]34C)[C@H](C)CC(=O)CC(C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C

Formula:

C32H44O9

Pathway:

Cell Cycle/Checkpoint,NF-_b,DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

CDK,NF-_B,DNA/RNA Synthesis,DNA/RNA Synthesis