Bioactivity:

7_, 25-dihydroxycholesterol (7_,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7_, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][

CAS nr:

64907-22-8

Purity:

98%

Molecular Weight:

418,65

SMILES:

[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)(C)O

Formula:

C27H46O3

Pathway:

GPCR/G Protein,Metabolism

Target:

EBI2/GPR183,Endogenous Metabolite