Bioactivity:

Alphitolic acid is a potent Hh/GLI signaling inhibitor, it shows an important relationship between Hh/GLI signaling inhibition, the decrease of BCL2, and cytotoxicity against cancer cells.

CAS nr:

19533-92-7

Purity:

98%

Molecular Weight:

472,7

SMILES:

CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@@]34C)C12)C(O)=O

Formula:

C30H48O4

Pathway:

Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,NF-_b,Apoptosis

Target:

Akt,Akt,NF-_B,p53