Bioactivity:

NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

CAS nr:

88039-46-7

Purity:

98%

Molecular Weight:

240,68

SMILES:

C=C(C(C1=CC=CC=C1Cl)O)C(OCC)=O

Formula:

C12H13ClO3

Pathway:

Target: