GSK-J4 T3100
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
GSK-J4 is a potent H3K27me3 demethylase inhibitor, with IC50s of 8.6 _M and 6.6 _M towards KDM6B and KDM6A respectively. It is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactiv
CAS nr:
1373423-53-0
Purity:
98%
Molecular Weight:
417,5
SMILES:
CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1
Formula:
C24H27N5O2
Pathway:
Apoptosis,Chromatin/Epigenetic
Target:
Apoptosis,Histone Demethylase
