Bioactivity:

SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both

CAS nr:

168835-82-3

Purity:

98%

Molecular Weight:

390,53

SMILES:

CC(C)c1cc(cc(C(C)C)c1O)\C=C(/C#N)C(=O)NCCCc1ccccc1

Formula:

C25H30N2O2

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

VEGFR,VEGFR