Bioactivity:

MK-2206 is a highly specific inhibitor of Akt1/2/3 (IC50: 8/12/65 nM in cell-free assays) and no effect on the activities of 250 other protein kinases.

CAS nr:

1032350-13-2

Purity:

98%

Molecular Weight:

480,39

SMILES:

Cl.Cl.NC1(CCC1)c1ccc(cc1)-c1nc2ccn3c(n[nH]c3=O)c2cc1-c1ccccc1

Formula:

C25H23Cl2N5O

Pathway:

Autophagy,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,Apoptosis

Target:

Autophagy,Akt,Akt,Apoptosis