Bioactivity:

Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM).

CAS nr:

150725-87-4

Purity:

98%

Molecular Weight:

473,54

SMILES:

CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1c(c(ncn1)OCCO)Oc1cc(ccc1)OC

Formula:

C23H27N3O6S

Pathway:

GPCR/G Protein

Target:

Endothelin Receptor