Bioactivity:

ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 _M and 9.7 _M in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.

CAS nr:

1443290-89-8

Purity:

98%

Molecular Weight:

374,27

SMILES:

CC1(C)C2=C(C=CC(Cl)=C2)N(CCC3=NN=NN3)C4=CC=C(Cl)C=C14

Formula:

C18H17Cl2N5

Pathway:

Proteases/Proteasome,Microbiology/Virology

Target:

HIV Protease,HIV Protease