APTO-253 T10352
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.
CAS nr:
916151-99-0
Purity:
98%
Molecular Weight:
367,38
SMILES:
Cc1[nH]c2ccc(F)cc2c1-c1nc2c([nH]1)c1cccnc1c1ncccc21
Formula:
C22H14FN5
Pathway:
MAPK,MAPK,Cell Cycle/Checkpoint,Apoptosis
Target:
KLF,KLF,c-Myc,Apoptosis
