Bioactivity:

MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice.�MBM-55 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM.�

CAS nr:

2083622-09-5

Purity:

98%

Molecular Weight:

498,55

SMILES:

NC(C(C=C1)=C(OCC2=CC=CC(F)=C2)C=C1C3=CN=C4N3C=CC(C5=CN(CCN(C)C)N=C5)=C4)=O

Formula:

C28H27FN6O2

Pathway:

PI3K/Akt/mTOR signaling,MAPK

Target:

S6 Kinase,S6 Kinase