Bioactivity:

CHIR98014 is a reversible, cell-permeable inhibitor of GSK3_ and GSK3_ (IC50s: 0.65 and 0.58 nM). Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50: 106 nM), potentiates insulin-dependent glucose transport in isolated musc

CAS nr:

T3074L

Purity:

98%

Molecular Weight:

559,23

SMILES:

NC1=NC(NCCNC2=NC=C(N3C=CN=C3)C(C4=CC=C(Cl)C=C4Cl)=N2)=CC=C1[N+]([O-])=O.[H]Cl.[H]Cl

Formula:

C20H19Cl4N9O2

Pathway:

Target: