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Bioactivity:
Takeda-6d, a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, inhibits B-RAF and VEGFR2 with IC50 of 7.0nM and 2.2nM.
CAS nr:
1125632-93-0
Purity:
98%
Molecular Weight:
548
SMILES:
Formula:
C27H19ClFN5O3S
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis
Target:
VEGFR,VEGFR