Bioactivity:

MKT-077 is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines (EC50s: 1.4-2.2 ﾵM in vitro) through its ability to inhibit members of the Hsp70 family of molecular chaperones.

CAS nr:

147366-41-4

Purity:

98%

Molecular Weight:

432

SMILES:

[Cl-].CCn1c(=Cc2cccc[n+]2CC)s\c(=C2\Sc3ccccc3N2C)c1=O

Formula:

C21H22ClN3OS2

Pathway:

Metabolism,Cytoskeletal Signaling

Target:

HSP,HSP