Bioactivity:

GRI 977143 is a selective lysophosphatidic acid 2 receptor non-lipid agonist (EC50 = 3.3 _M). Does not activate other LPA GPCRs at concentrations up to 10 _M. It also inhibits activation of caspases 3, 7, 8, and 9, Bax translocation, and PARP-1 cleavage.

CAS nr:

325850-81-5

Purity:

98%

Molecular Weight:

391,44

SMILES:

C1=CC=C(C(=C1)C(=O)O)SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O

Formula:

C22H17NO4S

Pathway:

Others

Target:

Others