Bioactivity:

compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range.

CAS nr:

2561476-24-0

Purity:

98%

Molecular Weight:

428,36

SMILES:

ClC1=CC(Cl)=C(C(N/2CC)=CSC2=N\C3=CC=C(S(=O)(N)=O)C=C3)C=C1

Formula:

C17H15Cl2N3O2S2

Pathway:

Metabolism

Target:

Carbonic Anhydrase