Bioactivity:

CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells.

CAS nr:

T10840

Purity:

98%

Molecular Weight:

602,04

SMILES:

CN1CCC(CNC2=CC(C3=CC=C(C)O3)=NC4=CC(OCCCN5CCCC5)=C(OC)C=C24)CC1.Cl.Cl.Cl

Formula:

C29H43Cl3N4O3

Pathway:

Chromatin/Epigenetic

Target:

DNA Methyltransferase